From the Editor:

Max Buja, Editor


September/October 2013 Issue (Volume 22, Number 5)

With the support of our new Elsevier publisher, Stacey Schick, we are going to be able to publish additional pages in the last two issues of Cardiovascular Pathology in 2013. This should allow for a reduction in the lag time from acceptance to full publication (print and electronic) from approximately 8 months to 6 months or less. Of course within a couple of weeks of acceptance, the manuscript will have already appeared in PubMed as an [Epub ahead of print].

The lead article in the September/October issue of CVP addresses the provocative topic of methodological considerations regarding documenting reduced plakoglobin immunoreactivity for the diagnosis of arrhythmogenic cardiomyopathy, and it is accompanied by two editorials on the subject. The issue also has three review articles as follows: A brief review of left ventricular assist devices with a recommended protocol for pathological evaluations; Cardiomyopathy in neurological disorders; and Vascular fibrosis in atherosclerosis. The other original articles address the following topics: complications of transcatheter aortic valve implantation (TAVI); primary endocardial fibroelastosis; topics in vascular pathology (atherosclerosis, intracranial aneurysms, intimal sarcomas); and experimental studies of hypertrophy, atrial fibrillation, myocarditis and pericardial fibrosis.

The Elsevier Marketing and Communications Vice President recently has broadcast interesting data on the top 5 most downloaded articles in 2013 from Cardiovascular Pathology (CVP) and the top 25 most downloaded articles in 2013 for all Elsevier pathology journals (EPJ). These are full-text downloads from the Science Direct platform during the period of January to June 2013. All 5 of the CVP articles are among the top 25 for all EPJ! The data are as follows: American Journal of Pathology 11 articles, Human Pathology 8 articles, Cardiovascular Pathology 5 articles and Journal of Molecular Diagnostics 1 article.

Here are the five most downloaded CVP articles listed by their CVP ranking with the overall EPJ ranking in parentheses:

1) Kemp CD, Conte JV. The pathophysiology of heart failure. Cardiovasc Pathol 2012;21:365-371. (EJP 1)

2) Asrih M, Steffens S. Emerging role of epigenetics and miRNA in diabetic cardiomyopathy. Cardiovasc Pathol 2013;22:117-125. (EJP 5)

3) Lan TH, huang XO, Tam HM. Vascular fibrosis in atherosclerosis. Cardiovasc Pathology [Epub ahead of Print] (EJP 7)

4) Buja LM. Myocardial ischemia and reperfusion injury. Cardiovasc Pathol 2005;14:170-175. (EJP 8)

5) Gimbrone MA Jr, Garciá-Cardeña G. Vascular endothelium, hemodynamics, and the pathobiology of atherosclerosis. Cardiovasc Pathol 2013;22:9-15. (EJP 22)

These data show that CVP is publishing articles that are attracting sufficient attention of internet browsers of the medical literature to lead them to download the full text of the articles and then presumably use the content provided in the articles. I think one factor in the strong showing of CVP articles is that cardiovascular disease has a broad and large constituency. However, I should point out that there is not a direct relationship between the download of an article and the subsequent citation of that article in another publication. At our last CVP Editorial Board meeting, the Elsevier publisher's report indicated that the 10 top CVP downloaded articles in 2012 had downloads ranging from 641 to 2,360. These numbers compare to the numbers for the top 13 CVP articles that contributed to our 2011 Impact Factor. These 13 articles that were published in 2009 and 2010 received 5 to 11 citations in subsequently published articles. So there is about a 100 to 200 fold difference between downloads and citations.

I will use myself as an illustration. I am pleased to see that my 2005 article on myocardial ischemia and reperfusion injury continues to receive significant downloads. But why is this article getting more downloads than my more recent article? - Buja LM, Weerasinghe P. Unresolved issues in myocardial reperfusion injury. Cardiovasc Pathol 2010;19:29-35. At the same time, the 2010 article received 5 citations (not all by me) contributing to the 2011 Impact Factor.

Here is another piece of information. The Kemp and Conte review article on the pathophysiology of heart failure is the topmost downloaded article for all of the Elsevier pathology journals in 2013 to date. This review article was solicited from the authors in conjunction with one of our SCVP Symposia. When I sent it out for peer review, the reviewers were lukewarm citing that the article covered well-known information on heart failure and didn't present major new insights. Nevertheless, I accepted the article because I did think it packaged a nice review of basic information, and furthermore, our Society had solicited it. Now the article is providing to be attracting many readers of the cardiovascular literature. I wouldn't be surprised if the figures from the article show up in lectures.

As one engaged for a long time in the scholarly process as an author, reviewer and editor, I find this analysis to be both interesting and humbling regarding understanding and predicting the outcomes of the usefulness and impact of published articles. As the people's philosopher, Yogi Berra, is said to have opined - prediction is very hard, especially about the future.


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L. Maximilian Buja, M.D.



Top Hottest CVP Articles in 2013 - view the most downloaded publications from Cardiovascular Pathology April to June 2013.

Read previous editor pages in the Archives.